Table 2.

Apoptosis genes up- and downregulated after ischemia (30 min) and 7d reperfusion compared with 7d sham-operated animals

Probe IDDescriptionSymbolMeanSD
Upregulated
1369262_atcaspase-8Casp83.50.2
1369407_attumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)Tnfrsf11b3.30.8
1387690_atcaspase 3Casp32.60.7
1369198_atapoptotic protease activating factor 1Apaf12.30.4
1368305_atcaspase 6Casp62.10.4
1390434_atTNFRSF1A-associated via death domainTradd1.90.1
1367856_atglucose-6-phosphate dehydrogenaseG6pdx1.80.2
1370112_atphosphatase and tensin homologPten1.80.1
1368856_atJanus kinase 2Jak21.80.3
1367715_attumor necrosis factor receptor superfamily, member 1aTnfrsf1a1.70.2
1387521_atprogrammed cell death 4Pdcd41.70.2
1389873_atapoptosis-associated speck-like protein containing a CARDAsc1.70.1
1367890_atcaspase 2Casp21.60.1
1387502_atserine/threonine kinase 17b (apoptosis-inducing)Stk17b1.60.3
1390386_atcaspase 3Casp31.60.1
1398286_atcysteine-sulfinate decarboxylaseCsad1.40.1
1371572_atamyloid beta (A4) precursor proteinApp1.40.1
1368118_atB-cell CLL/lymphoma 10Bcl101.40.1
1369879_a_attestis enhanced gene transcriptTegt1.30.0
1369084_a_atBcl-2-related ovarian killer proteinBok1.20.1
1387605_atcaspase 12Casp121.20.0
1370226_atcystatin BCstb1.20.0
1367465_atdefender against cell death 1Dad11.20.1
Downregulated
1372423_atp53 apoptosis-associated target−2.30.7
1372539_atcastration induced prostatic apoptosis-related protein 1Cipar1−1.70.3
1367641_atsuperoxide dismutase 1Sod1−1.60.1
1370962_atcastration induced prostatic apoptosis-related protein 1Cipar1−1.50.1
1370321_atprogrammed cell death 8 (apoptosis-inducing factor)Pdcd8−1.50.3
1369939_atcytochrome c, somaticCycs−1.50.1
1371638_atSimilar to zinc RING finger protein SAG, mRNA−1.30.2
1370923_atexpressed in non-metastatic cells 6, protein (nucleoside diphosphate kinase)Nme6−1.20.1
1386973_a_atmitogen activated protein kinase 8 interacting proteinMapk8ip−1.20.1
1369995_atFas-associated factor 1Faf1−1.20.0
  • Data presented indicate fold change (mean ± SD) in expression of ischemia (30 min) and reperfusion (7d) compared with corresponding sham-operated control sample. Data correspond to Fig. 4, clusters B and C.