Physiol. Genomics -- Table of Contents (February 11 2002, 8 [1])

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Editorial:

Dale J. Benos: Ethics, revisited
Physiol. Genomics 8: 1-2, 2002; 10.1152/physiolgenomics.00055.2001 [Full Text]

Editorial Focus:

SUSAN B. GLUECK and GERHARD HELDMAIER: Settling down for a long winter’s nap: Focus on "Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal"
Physiol. Genomics 8: 3-4, 2002; 10.1152/physiolgenomics.00118.2001 [Full Text]

Research Articles:

MICHAEL J. BUCK, TERESA L. SQUIRE, and MATTHEW T. ANDREWS: Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal
Physiol. Genomics 8: 5-13, 2002. First published November 27, 2001; 10.1152/physiolgenomics.00076.2001 [Abstract] [Full Text]

MING LO, KIAO LING LIU, JENNIFER-REBECCA CLEMITSON, JEAN SASSARD, and NILESH J. SAMANI: Chromosome 1 blood pressure QTL region influences renal function curve and salt sensitivity in SHR
Physiol. Genomics 8: 15-21, 2002. First published November 15, 2001; 10.1152/physiolgenomics.00057.2001 [Abstract] [Full Text]

CANWEN JIANG, HSIENWIE LU, KAREN A. VINCENT, SRINIVAS SHANKARA, ADAM J. BELANGER, SENG H. CHENG, GEOFFREY Y. AKITA, RALPH A. KELLY, MARK A. GOLDBERG, and RICHARD J. GREGORY: Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1 ${alpha}$
Physiol. Genomics 8: 23-32, 2002. First published November 15, 2001; 10.1152/physiolgenomics.00058.2001 [Abstract] [Full Text]

VICTOR RUIZ-VELASCO, STEPHEN R. IKEDA, and HENRY L. PUHL: Cloning, tissue distribution, and functional expression of the human G protein ß4-subunit
Physiol. Genomics 8: 41-50, 2002. First published November 20, 2001; 10.1152/physiolgenomics.00085.2001 [Abstract] [Full Text]

Ming-Chyuan Chen, Yi Zhou, and H. William Detrich, III: Zebrafish mitotic kinesin-like protein 1 (Mklp1) functions in embryonic cytokinesis
Physiol. Genomics 8: 51-66, 2002. First published November 27, 2001; 10.1152/physiolgenomics.00042.2001 [Abstract] [Full Text]

Henning Wittenburg, Frank Lammert, David Q.-H. Wang, Gary A. Churchill, Renhua Li, Guylaine Bouchard, Martin C. Carey, and Beverly Paigen: Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice
Physiol. Genomics 8: 67-77, 2002. First published December 18, 2001; 10.1152/physiolgenomics.00097.2001 [Abstract] [Full Text]

Perspective:

M. J. FINLEY AUSTIN and THANE KREINER: Integrating genomics technologies in health care: practice and policy challenges and opportunities
Physiol. Genomics 8: 33-40, 2002; 10.1152/physiolgenomics.00103.2001 [Abstract] [Full Text] [Supplemental Table]

Cover Caption:

Cover

Cover: Pattern of expression for the tyrosine hydroxylase gene in the brain, reconstructed using gene expression tomography (GET). In the image, the gene (represented here in pseudo-color) can be seen to be expressed in the locus coeruleus. Brain image is from the Mouse Brain Library and Atlas (http://www.mbl.org). GET should be a useful new methodology for high throughput acquisition of brain gene expression patterns. For further discussion, see the upcoming article (release 8.2): Brown VM, Ossadtchi A, Khan AH, Gambhir SS, Cherry SR, Leahy RM, and Smith DJ. Gene expression tomography. Physiol Genomics 8, 2002.