Physiol. Genomics -- Table of Contents (January 2009, 36 [2])

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Editorial Focus:

Howard M. Prentice: The major contribution of brain GABAergic function to anoxic survival
Physiol. Genomics 36: 59-60, 2009. First published November 25, 2008; doi:10.1152/physiolgenomics.90380.2008 [Full Text] [PDF]

Call For Papers: Comparative Genomics:

Stian Ellefsen, Kåre-Olav Stensløkken, Cathrine E. Fagernes, Tom A. Kristensen, and Göran E. Nilsson: Expression of genes involved in GABAergic neurotransmission in anoxic crucian carp brain (Carassius carassius)
Physiol. Genomics 36: 61-68, 2009. First published October 28, 2008; doi:10.1152/physiolgenomics.90301.2008 [Abstract] [Full Text] [PDF]

Brenda Lilly and Simone Kennard: Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling
Physiol. Genomics 36: 69-78, 2009. First published November 4, 2008; doi:10.1152/physiolgenomics.90318.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Research Articles:

George Argyropoulos, Adrian M. Stütz, Olha Ilnytska, Treva Rice, Margarita Teran-Garcia, D. C. Rao, Claude Bouchard, and Tuomo Rankinen: KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise
Physiol. Genomics 36: 79-88, 2009. First published November 4, 2008; doi:10.1152/physiolgenomics.00003.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]

Gustavo Helguera, Mansoureh Eghbali, Daniel Sforza, Tamara Y. Minosyan, Ligia Toro, and Enrico Stefani: Changes in global gene expression in rat myometrium in transition from late pregnancy to parturition
Physiol. Genomics 36: 89-97, 2009. First published November 11, 2008; doi:10.1152/physiolgenomics.00290.2007 [Abstract] [Full Text] [PDF]

R. D. Léandri, C. Archilla, L. C. Bui, N. Peynot, Z. Liu, C. Cabau, A. Chastellier, J. P. Renard, and V. Duranthon: Revealing the dynamics of gene expression during embryonic genome activation and first differentiation in the rabbit embryo with a dedicated array screening
Physiol. Genomics 36: 98-113, 2009. First published November 11, 2008; doi:10.1152/physiolgenomics.90310.2008 [Abstract] [Full Text] [PDF]

CALL FOR PAPERS: Computational Modeling of Physiological Systems:

Gudrun A. Brockmann, Shirng-Wern Tsaih, Christina Neuschl, Gary A. Churchill, and Renhua Li: Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight, or both
Physiol. Genomics 36: 114-126, 2009. First published November 4, 2008; doi:10.1152/physiolgenomics.90277.2008 [Abstract] [Full Text] [PDF]

Corrigendum:

: Corrigendum
Physiol. Genomics 36: 127, 2009; doi:10.1152/physiolgenomics.zh7-3309-corr.2009 [Full Text] [PDF]

Cover Caption:

Cover

Cover: shown is a female goldfish (Carassius auratus) in front of a carp/goldfish cDNA microarray developed in the AURATUS Goldfish Genomics project (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL3735). This platform was used to analyze the hypothalamic transcriptome in female goldfish injected with the antidepressant fluoxetine. Traces of this pharmaceutical have recently been detected in the aquatic environment. The study revealed effects on the reproductive axis in goldfish, in particular disruption of circulating estrogen. Analysis of the hypothalamic transcriptome identified the reproductive neuropeptide isotocin as being downregulated in the hypothalamus. Additional studies revealed that isotocin stimulates circulating estradiol, providing a potential mechanism for the observed decrease in estradiol. For details see Mennigen JA, Martyniuk CJ, Crump K, Xiong H, Zhao E, Popesku J, Anisman H, Cossins AR, Xia X, Trudeau VL. Effects of fluoxetine on the reproductive axis of female goldfish (Carassius auratus). Physiol Genomics 35: 273-282, 2008 (first published September 2, 2008) doi:10.1152/physiolgenomics.90263.2008.