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Contents: Volume 28, Release 2; 17 January 2007
[Index by Author]
[Editorial Board]
[Cover Caption]
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= article is free immediately upon publication
(all articles are free one year after publication)
Cover: Ultrafine mapping of Dyscalc1. A: localization of the quantitative trait locus, Dyscalc1 (black box), on mouse chromosome 7 between the simple sequence length polymorphism (SSLP) markers D7Mit270 and D7Mit230 using BXH-RI and congenic intercross analysis as published previously (4, 9). B: fine mapping of Dyscalc1 to 2 Mb using in silico mapping in BXH RI strains (BXH-7, BXH-8, BXH-9, and BXH-10). C: additional laboratory mouse strains allocate Dyscalc1 to ~1 Mb between the UT_7_38.436442 (39.5 Mb) and rs6379675 (40.5 Mb). D: genotyping of novel single nucleotide polymorphisms (SNPs) in NZB mice further decreased the region to 80 kb using PCR-single-strand conformation polymorphism (SSCP) analysis of genes flanking EMP-3 (highlighted in black). This 80-kb region contains the genes EMP-3, BC013491, and Abcc6. For details, see Aherrahrou Z, Doehring LC, Kaczmarek PM, Liptau H, Ehlers E-M, Pomarino A, Wrobel S, Götz A, Mayer B, Erdmann J, Schunkert H. Ultrafine mapping of Dyscalc1 to an 80-kb chromosomal segment on chromosome 7 in mice susceptible for dystrophic calcification. Physiol Genomics 28: 203-212, 2007; doi:10.1152/physiolgenomics.00133.2006.
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