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Contents: Volume 24, Release 1; 14 December 2005
[Index by Author]
[Editorial Board]
[Cover Caption]
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= article is free immediately upon publication
(all articles are free one year after publication)
Cover: Image registration identifies corresponding anatomy between control and mutant mouse groups. Within- and between-group shape differences are used to map regions of significantly differing anatomy, and these regions are highlighted and represented quantitatively by displacements and volume changes. Methodology is demonstrated for a partially characterized mouse mutation generated by N-ethyl-N-nitrosourea (ENU) mutagenesis that is a putative model of the human syndrome oculodentodigital dysplasia, caused by point mutations in the gene encoding connexin 43. For details, see Nieman BJ, Flenniken AM, Adamson SL, Henkelman RM, and Sled JG. Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography. Physiol Genomics 24: 154-162, 2006; doi: 10.1152/physiolgenomics.00217.2005.
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