Physiol. Genomics -- Table of Contents (October 17 2003, 15 [2])

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Research Articles:

Burns C. Blaxall, Rainer Spang, Howard A. Rockman, and Walter J. Koch: Differential myocardial gene expression in the development and rescue of murine heart failure
Physiol. Genomics 15: 105-114, 2003. First published July 15, 2003; 10.1152/physiolgenomics.00087.2003 [Abstract] [Full Text] [Supplemental Figures and References]

Maria Mirotsou, Coran M.H. Watanabe, Peter G. Schultz, Richard E. Pratt, and Victor J. Dzau: Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach
Physiol. Genomics 15: 115-126, 2003. First published August 5, 2003; 10.1152/physiolgenomics.00071.2003 [Abstract] [Full Text] [Supplenmental data]

K. C. Fertuck, J. E. Eckel, C. Gennings, and T. R. Zacharewski: Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol
Physiol. Genomics 15: 127-141, 2003. First published August 12, 2003; 10.1152/physiolgenomics.00058.2003 [Abstract] [Full Text] [Supplemental Tables]

James G. Dobson, John Fray, Jack L. Leonard, and Richard E. Pratt: Molecular mechanisms of reduced ß-adrenergic signaling in the aged heart as revealed by genomic profiling
Physiol. Genomics 15: 142-147, 2003. First published August 5, 2003; 10.1152/physiolgenomics.00076.2003 [Abstract] [Full Text] [Supplemental Data]

Beat Schmitt, Martin Flück, Jacques Décombaz, Roland Kreis, Chris Boesch, Matthias Wittwer, Franziska Graber, Michael Vogt, Hans Howald, and Hans Hoppeler: Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes
Physiol. Genomics 15: 148-157, 2003; 10.1152/physiolgenomics.00089.2003 [Abstract] [Full Text]

Toolbox:

Steven P. Suchyta, Sue Sipkovsky, Rachael Kruska, Abra Jeffers, Amanda McNulty, Matthew J. Coussens, Robert J. Tempelman, Robert G. Halgren, Peter M. Saama, Dale E. Bauman, Yves R. Boisclair, Jeanne L. Burton, Robert J. Collier, Edward J. DePeters, Theodore A. Ferris, Matthew C. Lucy, Mark A. McGuire, Juan F. Medrano, Thomas R. Overton, Timothy P. Smith, George W. Smith, Tad S. Sonstegard, James N. Spain, Donald E. Spiers, Jianbo Yao, and Paul M. Coussens: Development and testing of a high-density cDNA microarray resource for cattle
Physiol. Genomics 15: 158-164, 2003. First published September 16, 2003; 10.1152/physiolgenomics.00094.2003 [Abstract] [Full Text]

Cover Caption:

Cover

Cover: Histology of transplanted hearts and related gene expression profile. On day 7, transplanted cardiac grafts were harvested and processed for hematoxylin and eosin (H and E) staining. Top left: tolerizing allograft treated with mAbs 1G10 and GL1 on days 0-4. Top right: rejecting allograft. Bottom left: syngeneic isograft. Bottom right: segment of gene expression profile. Genes were clustered according to the similarity of their expression patterns. For further discussion, see article by Matsui Y, Saiura A, Sugawara Y, Sata M, Naruse K, Yagita H, Kohro T, Mataki C, Izumi A, Yamaguchi T, Minami T, Sakihama T, Ihara S, Aburatani H, Hamakubo T, Kodama T, and Makuuchi M. Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade. Physiol Genomics 15: 199-208, 2003. First published September 9, 2003; 10.1152/physiolgenomics.00086.2003.