Physiol. Genomics -- Table of Contents (June 24 2003, 14 [1])

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Editorial Focus:

Dörthe M. Katschinski and Susan B. Glueck: Hot worms can handle heavy metal. Focus on "HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans"
Physiol. Genomics 14: 1-2, 2003; 10.1152/physiolgenomics.00081.2003 [Full Text]

Reviews:

Colin K. L. Phoon and Daniel H. Turnbull: Ultrasound biomicroscopy-Doppler in mouse cardiovascular development
Physiol. Genomics 14: 3-15, 2003; 10.1152/physiolgenomics.00008.2003 [Abstract] [Full Text]

Research Articles:

Millet Treinin, Judith Shliar, Huaqi Jiang, Jo Anne Powell-Coffman, Zohar Bromberg, and Michal Horowitz: HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans
Physiol. Genomics 14: 17-24, 2003. First published April 9, 2003; 10.1152/physiolgenomics.00179.2002 [Abstract] [Full Text]

Thomas P. Cappola, Leslie Cope, Amy Cernetich, Lili A. Barouch, Khalid Minhas, Rafael A. Irizarry, Giovanni Parmigiani, Sarfraz Durrani, Tera Lavoie, Eric P. Hoffman, Shui Q. Ye, Joe G. N. Garcia, and Joshua M. Hare: Deficiency of different nitric oxide synthase isoforms activates divergent transcriptional programs in cardiac hypertrophy
Physiol. Genomics 14: 25-34, 2003. First published April 22, 2003; 10.1152/physiolgenomics.00156.2002 [Abstract] [Full Text] [Supplemental Tables]

Habtom Ressom, Dali Wang, and Padma Natarajan: Clustering gene expression data using adaptive double self-organizing map
Physiol. Genomics 14: 35-46, 2003. First published April 2, 2003; 10.1152/physiolgenomics.00138.2002 [Abstract] [Full Text]

Michelle M. Riehle, Albert F. Bennett, Richard E. Lenski, and Anthony D. Long: Evolutionary changes in heat-inducible gene expression in lines of Escherichia coli adapted to high temperature
Physiol. Genomics 14: 47-58, 2003. First published April 2, 2003; 10.1152/physiolgenomics.00034.2002 [Abstract] [Full Text] [Supplemental Data]

Baoan Ji, Xue-qing Chen, David E. Misek, Rork Kuick, Samir Hanash, Steve Ernst, Rebecca Najarian, and Craig D. Logsdon: Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator
Physiol. Genomics 14: 59-72, 2003. First published April 22, 2003; 10.1152/physiolgenomics.00174.2002 [Abstract] [Full Text]

Caroline Conte, Martin Ebeling, Anne Marcuz, Patrick Nef, and Pedro J. Andres-Barquin: Evolutionary relationships of the Tas2r receptor gene families in mouse and human
Physiol. Genomics 14: 73-82, 2003. First published May 6, 2003; 10.1152/physiolgenomics.00060.2003 [Abstract] [Full Text]

Clifford Wong, Nitish R. Mahapatra, Surin Chitbangonsyn, Payam Mahboubi, Manjula Mahata, Sushil K. Mahata, and Daniel T. O'Connor: The angiotensin II receptor (Agtr1a): functional regulatory polymorphisms in a locus genetically linked to blood pressure variation in the mouse
Physiol. Genomics 14: 83-93, 2003. First published April 15, 2003; 10.1152/physiolgenomics.00162.2002 [Abstract] [Full Text] [Supplemental Figures]

Cover Caption:

Cover

Gene expression changes in major lung proteins (CC10 and surfactant protein C), a key enzyme in the eukaryotic cell's response to oxidative stress (glutathione S-transferase), and cell cycle check point proteins (cyclin G and cyclin B1) resulting from hyperoxic lung damage. Cyclosporin A reversed the cyclin B1-mediated changes in gene expression. Background shows distal lung immunohistochemical detection of cyclin B1 after hyperoxia/cyclosporin A. Image by G. Doerman, E. Matthew, and J. Dedman. See related article by Matthew E, Kutcher L, and Dedman J. Physiol Genomics 14: 129-138, 2003. First published May 27, 2003; 10.1152/physiolgenomics.00130.2002.