Editorial Focus:

Stephen Welle and Susan B. Glueck

In for the long run: Focus on "Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart"
Physiol. Genomics 12: 71-72, 2003; 10.1152/physiolgenomics.00177.2002 [Full Text] [PDF]  

Research Articles:

Ondrej Seda, Ludmila Kazdova, Drahomira Krenova, and Vladimir Kren

Rosiglitazone fails to improve hypertriglyceridemia and glucose tolerance in CD36-deficient BN.SHR4 congenic rat strain
Physiol. Genomics 12: 73-78, 2003. First published November 12, 2002; 10.1152/physiolgenomics.00113.2002 [Abstract] [Full Text] [PDF]  

Christina K. Haston and Lap-Chee Tsui

Loci of intestinal distress in cystic fibrosis knockout mice
Physiol. Genomics 12: 79-84, 2003. First published November 19, 2002; 10.1152/physiolgenomics.00114.2002 [Abstract] [Full Text] [PDF]  

Chana Yagil, Norbert Hubner, Reinhold Kreutz, Detlev Ganten, and Yoram Yagil

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension
Physiol. Genomics 12: 85-95, 2003. First published November 19, 2002; 10.1152/physiolgenomics.00111.2002 [Abstract] [Full Text] [PDF]  

M. Steenman, Y.-W. Chen, M. Le Cunff, G. Lamirault, A. Varró, E. Hoffman, and J. J. Léger

Transcriptomal analysis of failing and nonfailing human hearts
Physiol. Genomics 12: 97-112, 2003. First published November 12, 2002; 10.1152/physiolgenomics.00148.2002 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Ellen O. Weinberg, Maria Mirotsou, Joseph Gannon, Victor J. Dzau, Richard T. Lee, and Richard E. Pratt

Sex dependence and temporal dependence of the left ventricular genomic response to pressure overload
Physiol. Genomics 12: 113-127, 2003. First published November 26, 2002; 10.1152/physiolgenomics.00046.2002 [Abstract] [Full Text] [PDF] [Supplemental Video]  

A. M. Bronikowski, P. A. Carter, T. J. Morgan, T. Garland, Jr, N. Ung, T. D. Pugh, R. Weindruch, and T. A. Prolla

Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart
Physiol. Genomics 12: 129-138, 2003. First published November 12, 2002; 10.1152/physiolgenomics.00082.2002 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Mingzhang Guo, Mack H. Wu, Ferenc Korompai, and Sarah Y. Yuan

Upregulation of PKC genes and isozymes in cardiovascular tissues during early stages of experimental diabetes
Physiol. Genomics 12: 139-146, 2003. First published November 19, 2002; 10.1152/physiolgenomics.00125.2002 [Abstract] [Full Text] [PDF]  

Hwa C. Lee, Manoj K. Patel, Dilawaar J. Mistry, Qingcai Wang, Sita Reddy, J. Randall Moorman, and J. Paul Mounsey

Abnormal Na channel gating in murine cardiac myocytes deficient in myotonic dystrophy protein kinase
Physiol. Genomics 12: 147-157, 2003. First published November 26, 2002; 10.1152/physiolgenomics.00095.2002 [Abstract] [Full Text] [PDF]  

Toolbox:

Chiara Romualdi, Stefania Bortoluzzi, Fabio d’Alessi, and Gian Antonio Danieli

IDEG6: a web tool for detection of differentially expressed genes in multiple tag sampling experiments
Physiol. Genomics 12: 159-162, 2003. First published November 12, 2002; 10.1152/physiolgenomics.00096.2002 [Abstract] [Full Text] [PDF]  

R. M. Murphy, K. K. O. Watt, D. Cameron-Smith, C. J. Gibbons, and R. J. Snow

Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR
Physiol. Genomics 12: 163-174, 2003. First published November 5, 2002; 10.1152/physiolgenomics.00060.2002 [Abstract] [Full Text] [PDF]  

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