Supplemental Tables

Eight tables in a variety of formats.

Files in this Data Supplement:

• Table S1 - Metabolic Syndrome Loci - PDF Loci associated with metabolic syndrome, and used to generate the starting set of candidates. The cytogenetic band identifier was used to define the interval used in the study. LOD scores from each study for each locus are shown in parentheses.
• Table S3 - Computational Methods - PDF Computational methods for disease gene prioritisation. This file contains a more detailed description of the methods used, including the thresholds and optimal parameters previously determined.
• Table S5 - Final Candidates Descriptions - PDF Candidate genes clustered according to protein-protein interactions, with gene function defined by UniProt/Swiss-Prot annotation.
• Table S8 - Final Candidate Genes Linkage Data - PDF This table details in which loci the selected candidate genes are found, and re-iterates the linkage data associated with those loci
• Table S2 - Starting Set of Candidate Genes - plain text This file contains a list of all candidate genes in the starting set, with chromosome, cytogenetic band and ensembl I.D. for each gene.
• Table S4 - Candidate Gene Selection - Excel A. Final selection of candidate genes common to the sets selected for: metabolic syndrome, white population, black population, male population and female population; B. Comparison of genes selected using weighted population phenotype frequency to unweighted analysis. These files illustrate the scoring system used for gene selection.
• Table S6 - DAVID Data - Excel This file presents the full DAVID analysis for the final candidate genes.
• Table S7 - REACTOME/SKYPAINTER Data - Excel This file presents the full Reactome/Skypainter analysis for the final candidate genes