Identification of novel transcriptional networks in response to treatment with the anticarcinogen 3H-1,2-dithiole-3-thione
Physiol. Genomics Huang et al.
24: 144
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Supplemental Data -
Supplemental Fig S1: Hierarchical clustering of ribosome constituents genes. All the expressed genes of cytosolic ribosome constituents (GO: 0005830) in the RG-U34A chip were clustered according to their expression profile across the 8 samples using dChip software. The 8 samples were correctly classified into D3T (sample D3T 1 - 4) group and vehicle control (sample Ctl 1 - 4) group based on the expression pattern of all cytosolic ribosome genes. More than 90% (56/61) of the cytosolic ribosome genes were classified into the upregulated Cluster U.
Note: Bold - Focus genes, the D3T regulated genes that were successfully mapped in the Ingenuity Pathway Knowledge Base; the 1st and 3rd network were displayed in Fig 3 & 4, respectively.